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SCOC Antibody

  • 货号：
    CSB-PA020854LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA020854LA01HU at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA020854LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA020854LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SCOC Polyclonal antibody
  • Uniprot No.：
    Q9UIL1
  • 基因名：
    SCOC
  • 别名：
    HRIHFB2072 antibody; Scoc antibody; SCOC_HUMAN antibody; SCOCO antibody; Short coiled coil protein antibody; Short coiled-coil protein antibody; UNC-69 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Short coiled-coil protein (1-121AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SCOC Antibody (CSB-PA020854LA01HU)，的标记方式是Non-conjugated。对于SCOC Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA020854LB01HU SCOC Antibody, HRP conjugated ELISA
    FITC CSB-PA020854LC01HU SCOC Antibody, FITC conjugated
    Biotin CSB-PA020854LD01HU SCOC Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Positive regulator of amino acid starvation-induced autophagy.
  • 基因功能参考文献：
    1. SCOC SNPs were associated with lifetime cannabis use, but the association did not reach genome-wide significance. [Meta-Analysis] PMID: 27023175
    2. SCOC forms a stable homogeneous complex with the coiled coil domain of FEZ1. SCOC dimerization and the SCOC surface residue R117 are important for this interaction. PMID: 24098481
    3. Studies indicate that FEZ1 (fasciculation and elongation protein zeta 1), SCOCO (short coiled-coil protein) and kinesins (kinesin heavy chain) are involved in biological transport process. PMID: 24116125
    4. The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037
  • 亚细胞定位：
    Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
  • 蛋白家族：
    SCOC family
  • 组织特异性：
    Widely expressed with highest levels in brain, heart and skeletal muscle.
  • 数据库链接：

    HGNC: 20335

    KEGG: hsa:60592

    STRING: 9606.ENSP00000377751

    UniGene: Hs.480815