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SCLY Antibody

  • 货号：
    CSB-PA020827LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA020827LA01HU diluted at 1:700 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SCLY Polyclonal antibody
  • Uniprot No.：
    Q96I15
  • 基因名：
    SCLY
  • 别名：
    hSCL antibody; Putative selenocysteine lyase antibody; SCL antibody; scly antibody; SCLY_HUMAN antibody; Selenocysteine lyase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Selenocysteine lyase protein (3-138AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SCLY Antibody (CSB-PA020827LA01HU)，的标记方式是Non-conjugated。对于SCLY Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA020827LB01HU SCLY Antibody, HRP conjugated ELISA
    FITC CSB-PA020827LC01HU SCLY Antibody, FITC conjugated
    Biotin CSB-PA020827LD01HU SCLY Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.
  • 基因功能参考文献：
    1. the X-ray crystal structure of human selenocysteine lyase and the key residue that provides the selenocysteine specificity PMID: 22295093
    2. A reaction mechanism whereby the Selenocysteine over Cysteine specificity is achieved using a combination of chemical and physico-mechanical control mechanisms. PMID: 22291978
    3. Results confirm that HCV core protein is associated with specific changes in mRNA expression, including the gene for selenocysteine lyase, which may be involved in the pathophysiology of hepatocellular carcinoma. PMID: 16925092
    4. PMID:10692412 concerns mostly mouse selenocysteine lyase, however, refers to the sequence of the N-terminal region of putative human protein. PMID: 10692412
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Class-V pyridoxal-phosphate-dependent aminotransferase family
  • 数据库链接：

    HGNC: 18161

    OMIM: 611056

    KEGG: hsa:51540

    STRING: 9606.ENSP00000254663

    UniGene: Hs.731909