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SCAMP2 Antibody

  • 货号：
    CSB-PA020751LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of A431 cells using CSB-PA020751LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA020751LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA020751LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SCAMP2 Polyclonal antibody
  • Uniprot No.：
    O15127
  • 基因名：
    SCAMP2
  • 别名：
    SCAMP2; Secretory carrier-associated membrane protein 2; Secretory carrier membrane protein 2
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Secretory carrier-associated membrane protein 2 protein (1-153AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SCAMP2 Antibody (CSB-PA020751LA01HU)，的标记方式是Non-conjugated。对于SCAMP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA020751LB01HU SCAMP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA020751LC01HU SCAMP2 Antibody, FITC conjugated
    Biotin CSB-PA020751LD01HU SCAMP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
  • 基因功能参考文献：
    1. this finding that SCAMP2 interacts with and regulates the subcellular distribution of both DAT and SERT suggests that interaction with SCAMP2 may constitute an important mechanism for coordinating cell surface expression of monoamine transporters. PMID: 21295544
    2. SCAMP2 plays an important role in the regulation of the subcellular distribution of SERT PMID: 16870614
    3. The strong correlation between SCAMP2 E interactions with PIP2 and inhibition of exocytosis, particularly by SC2-R204A, led us to propose that SCAMP2 interaction with PIP2 within the membrane interface regulates fusion pore formation during exocytosis. PMID: 17713930
    4. SCAMP2 regulates NHE5 transit through recycling endosomes and promotes its surface targeting in an Arf6-dependent manner. PMID: 19276089
  • 亚细胞定位：
    Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SCAMP family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 10564

    OMIM: 606912

    KEGG: hsa:10066

    STRING: 9606.ENSP00000268099

    UniGene: Hs.458917