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Reg3a Antibody

  • 货号：
    CSB-PA019548LA01RA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Rattus norvegicus (Rat) Reg3a Polyclonal antibody
  • Uniprot No.：
    P35231
  • 基因名：
    Reg3a
  • 别名：
    Reg3a antibody; Pap2 antibody; Reg3 antibody; Regenerating islet-derived protein 3-alpha antibody; REG-3-alpha antibody; Islet of Langerhans regenerating protein 3 antibody; REG 3 antibody; Lithostathine 3 antibody; Pancreatitis-associated protein 2 antibody; RegIII antibody; Regenerating islet-derived protein III-alpha antibody; Reg III-alpha) [Cleaved into: Regenerating islet-derived protein 3-alpha 16.5 kDa form; Regenerating islet-derived protein 3-alpha 15 kDa form] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Rat
  • 免疫原：
    Recombinant Rat Regenerating islet-derived protein 3-alpha protein (26-174AA)
  • 免疫原种属：
    Rattus norvegicus (Rat)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Reg3a Antibody (CSB-PA019548LA01RA)，的标记方式是Non-conjugated。对于Reg3a Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019548LB01RA Reg3a Antibody, HRP conjugated ELISA
    FITC CSB-PA019548LC01RA Reg3a Antibody, FITC conjugated
    Biotin CSB-PA019548LD01RA Reg3a Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
  • 基因功能参考文献：
    1. The pancreas reacts to remote lesions and septic insults in mice and rats with increased PSP synthesis, while PAP is selectively responsive to septic events. Furthermore, our results suggest that serum PSP in septic patients is predominantly derived through an acute phase response of the pancreas. PMID: 28415799
    2. Findings suggest that islet neogenesis-associated protein (INGAP) exerts a positive modulatory effect on beta-cell mass and its secretory function in fetal and neonatal rats, thus becoming a new component in the multifactorial regulation of such processes. PMID: 23303201
    3. After duodenal-jejunal bypass, the level of Reg3alpha and -3beta were not changed in bypassed duodenum in morbidly obese Zucker fatty rats. PMID: 23370676
    4. Letter: aggregation status of PAP1 and PAP2 could change their role in regulating the inflammation in acute pancreatitis. PMID: 21926556
    5. There is a tight spatial and temporal association between pre-inflammatory changes or inflammation and PAP-expression. PMID: 15100001
    6. Small interfering RNA-mediated gene knockdown of PAP worsens pancreatitis. Differences in gene knockdown technology may provide different approaches to study gene function. PMID: 18437087
    7. Pancreatitis-associated protein 2 stimulates macrophage activity and likely modulates the inflammatory environment of pancreatitis PMID: 18641332
    8. preincubation with select rPAP2 mutant proteins affect translocation of this transcription factor into the nucleus PMID: 18641333

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  • 相关疾病：
    Overexpressed during the acute phase of pancreatitis.
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Low expression found in healthy pancreas.
  • 数据库链接：

    KEGG: rno:171162

    STRING: 10116.ENSRNOP00000008468

    UniGene: Rn.11222