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RTKN2 Antibody

  • 货号：
    CSB-PA020566GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8IZC4
  • 基因名：
    RTKN2
  • 别名：
    RTKN2 antibody; PLEKHK1Rhotekin-2 antibody; Pleckstrin homology domain-containing family K member 1 antibody; PH domain-containing family K member 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human RTKN2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play an important role in lymphopoiesis.
  • 基因功能参考文献：
    1. RTKN2 was upregulated in human bladder cancer tissues and cell lines. Silencing of RTKN2 inhibited proliferation and invasion, and induced cell apoptosis. In addition, knockdown of RTKN2 arrested the cell cycle at the G1 phase via inhibition of the expression of cell cycle-associated proteins. PMID: 27082503
    2. RTKN2 was overexpressed in HCC tissues. RTKN2 served an important role in tumorigenesis and metastasis of HCC. PMID: 27081789
    3. miR-1246 promotes UVB-induced apoptosis by downregulating RTKN2 expression and that UVB-upregulated miR-1246 released RTKN2-dependent resistance to UVB-induced apoptosis by targeting RTKN2 post-transcriptionally in keratinocyte cells. PMID: 24880483
    4. we identified two gene loci associated with rheumatoid arthritis susceptibility- NFKBIE and RTKN2 PMID: 23028356
    5. Cloning and characterization of gene expression of rhotekin-2. PMID: 15504364

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  • 组织特异性：
    Expressed in lymphocytes, CD4 positive T-cells and bone marrow-derived cells. Also expressed in lung, colon, thymus and brain.
  • 数据库链接：

    HGNC: 19364

    KEGG: hsa:219790

    UniGene: Hs.58559