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RSC2 Antibody

  • 货号：
    CSB-PA312369XA01SVG
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:RSC2 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 32 kDa
      Observed band size: 35 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RSC2 Antibody Polyclonal antibody
  • Uniprot No.：
    Q06488
  • 基因名：
    RSC2 Antibody
  • 别名：
    Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2) RSC2 YLR357W L9638.1
  • 宿主：
    Rabbit
  • 反应种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) RSC2 protein (401-641aa)
  • 免疫原种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is involved in meiotic sporulation through regulating IME2 expression, and is also essential for 2-micron plasmid maintenance and for normal REP1 protein localization.
  • 基因功能参考文献：
    1. Results show that H4 acetylation by the NuA4 complex and RSC2 are both required for gap-induced sister chromatid recombination. PMID: 25132173
    2. This study uncovered a direct interaction between the Rsc2 BAH domain and histone H3 and led to the identification of an interaction interface that is conserved in a subset of Rsc-like BAH domains. PMID: 23907388
    3. Data show that RSC1 and RSC2 are haploinsufficient for spore formation in a smk1 hypomorph. PMID: 15302824
    4. RSC2 may function through the tRNA element to restric the spread of silencing PMID: 16079223
  • 亚细胞定位：
    Nucleus. Note=Localizes to centromeric and flanking chromatin. Association with these loci is dependent on STH1.
  • 蛋白家族：
    RSC1 family
  • 数据库链接：

    KEGG: sce:YLR357W

    STRING: 4932.YLR357W