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RRS1 Antibody

  • 货号：
    CSB-PA004028
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using RRS1 Polyclonal Antibody
    • Western blot analysis of HELA KB SH-SY5Y lysis using RRS1 antibody.
  • 其他：

产品详情

  • Uniprot No.：
    Q15050
  • 基因名：
    RRS1
  • 别名：
    Homolog of yeast ribosome biogenesis regulator antibody; Homolog of yeast ribosome biogenesis regulatory protein RRS1 antibody; KIAA0112 antibody; OTTHUMP00000227420 antibody; Ribosome biogenesis regulatory protein homolog antibody; Ribosome biogenesis regulatory protein RRS1 homolog antibody; RRR antibody; rrs1 antibody; RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) antibody; RRS1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RRS1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
  • 基因功能参考文献：
    1. These results suggest that the RRS1 gene plays a critical role in cell proliferation, colony formation, cell apoptosis and cell cycle distribution in human HCC cells, and that silencing of RRS1 by RNAi is a promising therapeutic approach for the treatment of HCC, and should be further developed PMID: 28849112
    2. RNA interference experiments revealed that RRS1-depleted cells show abnormalities in chromosome alignment and spindle organization, which result in mitotic delay. PMID: 19465021
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    RRS1 family
  • 数据库链接：

    HGNC: 17083

    KEGG: hsa:23212

    STRING: 9606.ENSP00000322396

    UniGene: Hs.71827