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RPS7 Antibody

  • 货号:
    CSB-PA020476LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • IHC image of CSB-PA020476LA01HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA020476LA01HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated ABC system.
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) RPS7 Polyclonal antibody
  • Uniprot No.:
    P62081
  • 基因名:
    RPS7
  • 别名:
    40S ribosomal protein S7 antibody; DBA8 antibody; Ribosomal protein S7 antibody; RPS 7 antibody; rps7 antibody; RS7_HUMAN antibody; S7 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human 40S ribosomal protein S7 protein (1-194AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,RPS7 Antibody (CSB-PA020476LA01HU),的标记方式是Non-conjugated。对于RPS7 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA020476LB01HU RPS7 Antibody, HRP conjugated ELISA
    FITC CSB-PA020476LC01HU RPS7 Antibody, FITC conjugated
    Biotin CSB-PA020476LD01HU RPS7 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Required for rRNA maturation.
  • 基因功能参考文献:
    1. BCCIPbeta interacts with the central basic region in S7 protein and regulates the extraribosomal distribution of S7. PMID: 28510697
    2. RPS7 role in cell proliferation in the context of Hepatitis B virus-related hepatocellular carcinoma.SIRT7 trans-represses RPS7 gene in the presence of HBx protein. PMID: 26442981
    3. Low expression of RPS7 is associated with colorectal cancer. PMID: 26735579
    4. Knockdown of RPS7 resulted in increased expression of P85alpha, P110alpha, and AKT2. PMID: 24244431
    5. The study found two ribosomal proteins, RPS7 and RPL13A that interact with the HMG (high-mobility group) box domain of SRY. PMID: 21114473
    6. S7 binds to MDM2, in vitro and in vivo, and the interaction between MDM2 and S7 leads to modulation of MDM2-p53 binding by forming a ternary complex among MDM2, p53 and S7. PMID: 17310983

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  • 相关疾病:
    Diamond-Blackfan anemia 8 (DBA8)
  • 亚细胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族:
    Eukaryotic ribosomal protein eS7 family
  • 数据库链接:

    HGNC: 10440

    OMIM: 603658

    KEGG: hsa:6201

    STRING: 9606.ENSP00000339095

    UniGene: Hs.534346