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RPS23 Antibody

  • 货号：
    CSB-PA040276
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P62266
  • 基因名：
    RPS23
  • 别名：
    40S ribosomal protein S23 antibody; FLJ35016 antibody; Homolog of yeast ribosomal protein S28 antibody; Ribosomal protein S23 antibody; RPS 23 antibody; RPS23 antibody; RS23_HUMAN antibody; S23 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Ribosomal Protein S23.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy.
  • 基因功能参考文献：
    1. A missense mutation is reported in two unrelated individuals with microcephaly, hearing loss, and overlapping dysmorphic features. PMID: 28257692
    2. Report dysregulated expression of RPS23 in disc degeneration. PMID: 25893343
    3. Rps23p hydroxylation can either increase or decrease translational accuracy in a stop codon context-dependent manner. PMID: 24550462
  • 相关疾病：
    Brachycephaly, trichomegaly, and developmental delay (BTDD)
  • 亚细胞定位：
    Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.
  • 蛋白家族：
    Universal ribosomal protein uS12 family
  • 数据库链接：

    HGNC: 10410

    OMIM: 603683

    KEGG: hsa:6228

    STRING: 9606.ENSP00000296674

    UniGene: Hs.527193