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RPIA Antibody

  • 货号：
    CSB-PA020104GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P49247
  • 基因名：
    RPIA
  • 别名：
    EC 5.3.1.6 antibody; MGC103524 antibody; Phosphoriboisomerase A antibody; Phosphoriboisomerase antibody; Ribose 5 phosphate isomerase antibody; ribose 5-phosphate epimerase antibody; ribose 5-phosphate isomerase A antibody; Ribose-5-phosphate isomerase antibody; RPI antibody; rpiA antibody; RPIA_HUMAN antibody; zgc:103524 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human RPIA
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. The results are consistent with a model in which RPIA suppresses autophagy and LC3 processing by modulation of redox signaling. PMID: 27328773
    2. CRC cells that overexpressed miR124 or with knockdown of RPIA or PRPS1 had reduced DNA synthesis and proliferation, whereas cells incubated with an inhibitor of miR124 had significantly increased DNA synthesis and proliferation and formed more colonies. PMID: 26248089
    3. In this work, through an in silico comparative analysis between the genomes of Leishmania major and Homo sapiens, the enzyme ribose 5-phosphate isomerase (R5PI) was indicated as a promising molecular target. PMID: 25528729
    4. Study provides new insight into the molecular mechanisms by which RPIA overexpression can induce oncogenesis in hepatocellular carcinoma. PMID: 25429733
    5. RPI is the second known inborn error in the reversible phase of the pentose-phosphate-pathway, confirming that defects in pentose and polyol metabolism constitute a new area of inborn metabolic disorders PMID: 14988808

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  • 相关疾病：
    Ribose 5-phosphate isomerase deficiency (RPID)
  • 蛋白家族：
    Ribose 5-phosphate isomerase family
  • 数据库链接：

    HGNC: 10297

    OMIM: 180430

    KEGG: hsa:22934

    STRING: 9606.ENSP00000283646

    UniGene: Hs.469264