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RORB Antibody

  • 货号：
    CSB-PA821694LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: U87 whole cell lysate
      All lanes: RORB antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 54, 53 kDa
      Observed band size: 54 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RORB Polyclonal antibody
  • Uniprot No.：
    Q92753
  • 基因名：
    RORB
  • 别名：
    bA133M9.1 antibody; NR1F2 antibody; Nuclear receptor ROR-beta antibody; Nuclear receptor RZR beta antibody; Nuclear receptor RZR-beta antibody; Nuclear receptor subfamily 1 group F member 2 antibody; OTTHUMP00000021486 antibody; RAR related orphan receptor B antibody; RAR related orphan receptor beta antibody; Retinoic acid binding receptor beta antibody; Retinoid-related orphan receptor-beta antibody; ROR BETA antibody; Rorb antibody; RORB_HUMAN antibody; RZR BETA antibody; RZRB antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Nuclear receptor ROR-beta protein (1-269AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RORB Antibody (CSB-PA821694LA01HU)，的标记方式是Non-conjugated。对于RORB Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA821694LB01HU RORB Antibody, HRP conjugated ELISA
    FITC CSB-PA821694LC01HU RORB Antibody, FITC conjugated
    Biotin CSB-PA821694LD01HU RORB Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity.; Isoform 1 is critical for hindlimb motor control and for the differentiation of amacrine and horizontal cells in the retina. Regulates the expression of PTF1A synergistically with FOXN4.
  • 亚细胞定位：
    Nucleus, nucleoplasm.
  • 蛋白家族：
    Nuclear hormone receptor family, NR1 subfamily
  • 数据库链接：

    HGNC: 10259

    OMIM: 601972

    STRING: 9606.ENSP00000366093

    UniGene: Hs.494178