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RNMTL1 Antibody

  • 货号：
    CSB-PA019903GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9HC36
  • 基因名：
    MRM3
  • 别名：
    16S rRNA (guanosine(1370)-2'-O)-methyltransferase antibody; 16S rRNA [Gm1370] 2'-O-methyltransferase antibody; 4833420N02Rik antibody; AI255153 antibody; FLJ10581 antibody; HC90 antibody; MRM3 antibody; MRM3_HUMAN antibody; Putative RNA methyltransferase antibody; RMTL1 antibody; RNA methyltransferase like 1 antibody; RNA methyltransferase like protein 1 antibody; RNA methyltransferase-like protein 1 antibody; RP23-147P4.7 antibody; rRNA methyltransferase 3, mitochondrial antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human RNMTL1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
  • 基因功能参考文献：
    1. MRM2 and MRM3 are human mitochondrial methyltransferases involved in the modification of 16S rRNA and are important factors for the biogenesis and function of the large subunit of the mitochondrial ribosome. PMID: 25009282
    2. Data show that 2'-O-methyltransferases MRM1, MRM2, and RNMTL1 are responsible for modification of large subunit rRNA at residues G1145, U1369, and G1370, respectively. PMID: 25074936
    3. The ATF/CREB site is the key element for transcription of this protein found on human chromosome 17. PMID: 12296377
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family
  • 组织特异性：
    Expressed at same level in normal liver and hepatocarcinoma.
  • 数据库链接：

    HGNC: 18485

    OMIM: 612600

    KEGG: hsa:55178

    STRING: 9606.ENSP00000306080

    UniGene: Hs.182729