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RMND1 Antibody

  • 中文名称：
    RMND1兔多克隆抗体
  • 货号：
    CSB-PA882123LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: MCF-7 whole cell lysate, HEK293 whole cell lysate, Mouse skeletal muscle tissue
      All lanes: RMND1 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 28, 24 kDa
      Observed band size: 52 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA882123LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA882123LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA882123LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RMND1 Polyclonal antibody
  • Uniprot No.：
    Q9NWS8
  • 基因名：
    RMND1
  • 别名：
    bA351K16 antibody; bA351K16.3 antibody; C6orf96 antibody; chromosome 6 open reading frame 96 antibody; FLJ20627 antibody; MGC117362 antibody; MGC149570 antibody; MGC882602 antibody; required for meiotic nuclear division 1 homolog (S. cerevisiae) antibody; Required for meiotic nuclear division protein 1 homolog antibody; Rmnd1 antibody; RMND1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Required for meiotic nuclear division protein 1 homolog protein (35-160AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RMND1 Antibody (CSB-PA882123LA01HU)，的标记方式是Non-conjugated。对于RMND1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA882123LB01HU RMND1 Antibody, HRP conjugated ELISA
    FITC CSB-PA882123LC01HU RMND1 Antibody, FITC conjugated
    Biotin CSB-PA882123LD01HU RMND1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
  • 基因功能参考文献：
    1. Hearing impairment and renal failure are associated with RMND1 mutations. PMID: 26395190
    2. Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] PMID: 26928228
    3. Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome. PMID: 23022098
    4. The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins. PMID: 23022099
  • 相关疾病：
    Combined oxidative phosphorylation deficiency 11 (COXPD11)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    RMD1/sif2 family
  • 数据库链接：

    HGNC: 21176

    OMIM: 614917

    KEGG: hsa:55005

    STRING: 9606.ENSP00000356272

    UniGene: Hs.486835