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RIDA Antibody

  • 货号：
    CSB-PA010744LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA010744LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA010744LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RIDA Polyclonal antibody
  • Uniprot No.：
    P52758
  • 基因名：
    RIDA
  • 别名：
    14.5 kDa translational inhibitor protein antibody; 2-iminobutanoate/2-iminopropanoate deaminase antibody; Heat responsive protein 12 antibody; Heat-responsive protein 12 antibody; Hrsp12 antibody; p14.5 antibody; Perchloric acid soluble protein antibody; PSP antibody; Reactive intermediate imine deaminase A homolog antibody; Ribonuclease UK114 antibody; RIDA antibody; Translational inhibitor p14.5 antibody; Translational inhibitor protein p14.5 antibody; UK114 antibody; UK114 antigen homolog antibody; UK114_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 2-iminobutanoate/2-iminopropanoate deaminase protein (2-137AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RIDA Antibody (CSB-PA010744LA01HU)，的标记方式是Non-conjugated。对于RIDA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010744LB01HU RIDA Antibody, HRP conjugated ELISA
    FITC CSB-PA010744LC01HU RIDA Antibody, FITC conjugated
    Biotin CSB-PA010744LD01HU RIDA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.; Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage.
  • 基因功能参考文献：
    1. x-ray crystallography study of p14.5 PMID: 14997576
    2. analysis of ligand binding sites of protein p14.5 PMID: 16198412
  • 亚细胞定位：
    Cytoplasm. Nucleus. Peroxisome. Mitochondrion.
  • 蛋白家族：
    RutC family
  • 组织特异性：
    Expressed predominantly in liver and kidney. Lower levels in lung and brain.
  • 数据库链接：

    HGNC: 16897

    OMIM: 602487

    KEGG: hsa:10247

    STRING: 9606.ENSP00000254878

    UniGene: Hs.18426