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RHOT2 Antibody

  • 货号：
    CSB-PA810289LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA810289LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA810289LA01HU diluted at 1:400 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RHOT2 Polyclonal antibody
  • Uniprot No.：
    Q8IXI1
  • 基因名：
  • 别名：
    ARHT2 antibody; C16orf39 antibody; hMiro 2 antibody; hMiro-2 antibody; hMiro2 antibody; MIRO-2 antibody; MIRO2_HUMAN antibody; Mitochondrial Rho GTPase 2 antibody; Ras homolog gene family member T2 antibody; RASL antibody; RHOT2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial Rho GTPase 2 protein (84-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RHOT2 Antibody (CSB-PA810289LA01HU)，的标记方式是Non-conjugated。对于RHOT2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA810289LB01HU RHOT2 Antibody, HRP conjugated ELISA
    FITC CSB-PA810289LC01HU RHOT2 Antibody, FITC conjugated
    Biotin CSB-PA810289LD01HU RHOT2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
  • 基因功能参考文献：
    1. The Miro2-mediated mitochondrial transport in neurons and recently highlighted involvement of Miro2 proteins in mitochondrial turnover, emerging as a key process affected in neurodegeneration. PMID: 24256248
    2. Miro proteins serve as a [Ca(2+)](c)-sensitive switch and bifunctional regulator for both the motility and fusion-fission dynamics of the mitochondria. PMID: 19098100
  • 亚细胞定位：
    Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Colocalizes with MGARP and RHOT2 at the mitochondria.
  • 蛋白家族：
    Mitochondrial Rho GTPase family
  • 组织特异性：
    Ubiquitously expressed. Highly expressed in heart, liver, skeletal muscle, kidney and pancreas.
  • 数据库链接：

    HGNC: 21169

    OMIM: 613889

    KEGG: hsa:89941

    STRING: 9606.ENSP00000321971

    UniGene: Hs.513242