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RGS18 Antibody

  • 货号：
    CSB-PA019649LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA019649LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA019649LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RGS18 Polyclonal antibody
  • Uniprot No.：
    Q9NS28
  • 基因名：
    RGS18
  • 别名：
    Regulator of G protein signalling 13 antibody; Regulator of G Protein Signalling 18 antibody; Regulator of G-protein signaling 18 antibody; RGS 18 antibody; RGS13 antibody; RGS18 antibody; RGS18_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Regulator of G-protein signaling 18 protein (28-84AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RGS18 Antibody (CSB-PA019649LA01HU)，的标记方式是Non-conjugated。对于RGS18 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019649LB01HU RGS18 Antibody, HRP conjugated ELISA
    FITC CSB-PA019649LC01HU RGS18 Antibody, FITC conjugated
    Biotin CSB-PA019649LD01HU RGS18 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha-2, G(i) alpha-3 and G(q) alpha.
  • 基因功能参考文献：
    1. These findings indicate cross-talk between platelet activation and inhibition pathways at the level of RGS18 and Gq. PMID: 22234696
    2. Data show that that SPL/RGS/SHP1 complexes are present in resting platelets where constitutive phosphorylation of SPL(Y398) creates an atypical binding site for SHP-1. PMID: 22210881
    3. molecular cloning and characterization of RGS18 as a regulator of G protein signalling in human platelets PMID: 11955952
    4. gene mapped to chromosome 1. PMID: 16484797
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver.
  • 数据库链接：

    HGNC: 14261

    OMIM: 607192

    KEGG: hsa:64407

    STRING: 9606.ENSP00000356430

    UniGene: Hs.440890