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RGL2 Antibody

  • 货号：
    CSB-PA019625LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, Mouse heart tissue, Rat liver tissue
      All lanes: RGL2 antibody at 3.2μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 84, 51 kDa
      Observed band size: 84 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA019625LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA019625LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RGL2 Polyclonal antibody
  • Uniprot No.：
    O15211
  • 基因名：
  • 别名：
    GDS related protein antibody; HKE1.5 antibody; KE1.5 antibody; RAB2L antibody; Ral guanine nucleotide dissociation stimulator-like 2 antibody; RalGDS-like 2 antibody; RalGDS-like factor antibody; Ras-associated protein RAB2L antibody; RGL2 antibody; RGL2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse, Rat
  • 免疫原：
    Recombinant Human Ral guanine nucleotide dissociation stimulator-like 2 protein (145-328AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RGL2 Antibody (CSB-PA019625LA01HU)，的标记方式是Non-conjugated。对于RGL2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019625LB01HU RGL2 Antibody, HRP conjugated ELISA
    FITC CSB-PA019625LC01HU RGL2 Antibody, FITC conjugated
    Biotin CSB-PA019625LD01HU RGL2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
  • 基因功能参考文献：
    1. SAMD9, an IFN-gamma-responsive protein, interacts with RGL2 to diminish the expression of EGR1, a protein of direct relevance to the pathogenesis of ectopic calcification and inflammation. PMID: 21160498
    2. Rgl2 and RalB both localized to the leading edge, and this localization of RalB was dependent on endogenous Rgl2 expression. PMID: 20801877
    3. RGL2 is phosphorylated by PKA and phosphorylation reduces the ability of RGL2 to bind H-Ras. results of the present study indicate that Ras may distinguish between the different RalGDS family members by their phosphorylation by PKA. PMID: 18540861
  • 数据库链接：

    HGNC: 9769

    OMIM: 602306

    KEGG: hsa:5863

    STRING: 9606.ENSP00000420211

    UniGene: Hs.509622