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RELT Antibody

  • 货号：
    CSB-PA070058
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q969Z4
  • 基因名：
    RELT
  • 别名：
    Receptor expressed in lymphoid tissues antibody; Relt antibody; TNFRSF19L antibody; TR19L_HUMAN antibody; Tumor necrosis factor receptor superfamily member 19L antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human RELT.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation.
  • 基因功能参考文献：
    1. Collectively, this study provides more insights into RELT expression, RELT family member function, and the mechanism of RELT-induced death. PMID: 28688764
    2. report that overexpression of RELT or its homologues RELL1 and RELL2 in HEK 293 epithelial cells results in cell death with morphological characteristics consistent with the activation of an apoptotic pathway. PMID: 19969290
    3. Receptor expressed in lymphoid tissue (RELT) and its novel homologues RELL1 and RELL2 co-localize with one another at the plasma membrane. PMID: 16389068
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族：
    RELT family
  • 组织特异性：
    Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
  • 数据库链接：

    HGNC: 13764

    OMIM: 611211

    KEGG: hsa:84957

    STRING: 9606.ENSP00000064780

    UniGene: Hs.533720