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RBAK Antibody

  • 货号：
    CSB-PA003952
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HepG2 cells using RBAK Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NYW8
  • 基因名：
    RBAK
  • 别名：
    hRBaK antibody; Hypothetical protein RBAK antibody; RB associated KRAB zinc finger antibody; RB-associated KRAB repressor antibody; RB-associated KRAB zinc finger protein antibody; RBAK antibody; RBAK_HUMAN antibody; Zinc finger protein 769 antibody; ZNF 769 antibody; ZNF769 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human RBAK.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May repress E2F-dependent transcription. May promote AR-dependent transcription.
  • 基因功能参考文献：
    1. Studies indicate that data on the regulatory functions of the KRAB-ZFP in embryonic development and tumorgenesis will benefit the understanding of biological roles of KRAB-ZFP in different physiological and pathological states. PMID: 20466629
    2. RBaK interacts with the androgen receptor and increases its transcriptional activity. PMID: 14664718
    3. study found no evidence of mutations in the coding sequence and splice sites of RBaK in association with familial hyperaldosteronism type II PMID: 17121540
    4. The role of RBaK, PMS2, and GNA12 in the inheritance of familial hyperaldosteronism type II were studied. PMID: 18307725
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
  • 数据库链接：

    HGNC: 17680

    OMIM: 608191

    KEGG: hsa:57786

    STRING: 9606.ENSP00000275423

    UniGene: Hs.396178