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RALY Antibody

  • 货号：
    CSB-PA008276
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of CoLo cells using Raly Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKM9
  • 基因名：
    RALY
  • 别名：
    Autoantigen p542 antibody; Heterogeneous nuclear ribonucleoprotein C-like 2 antibody; hnRNP associated with lethal yellow protein homolog antibody; hnRNP core protein C-like 2 antibody; MGC117312 antibody; P542 antibody; RALY antibody; RALY_HUMAN antibody; RNA binding protein (autoantigenic hnRNP associated with lethal yellow) antibody; RNA binding protein (autoantigenic) antibody; RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)) antibody; RNA-binding protein Raly antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Raly.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis. May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
  • 基因功能参考文献：
    1. hnRNP RALY regulates PMID: 28972179
    2. RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells PMID: 28733251
    3. RALY is a poly-U binding protein and as a regulator of H1FX and ANXA1 in mammalian cells. PMID: 28379492
    4. People with lower level of RALYL expression had a poorer survival rate. PMID: 22994768
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    RRM HNRPC family, RALY subfamily
  • 组织特异性：
    Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
  • 数据库链接：

    HGNC: 15921

    OMIM: 614663

    KEGG: hsa:22913

    STRING: 9606.ENSP00000246194

    UniGene: Hs.136947