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RAI14 Antibody

  • 货号：
    CSB-PA868376LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA868376LA01HU diluted at 1:700 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RAI14 Polyclonal antibody
  • Uniprot No.：
    Q9P0K7
  • 基因名：
    RAI14
  • 别名：
    Ankycorbin antibody; Ankyrin repeat and coiled coil structure containing protein antibody; Ankyrin repeat and coiled-coil structure-containing protein antibody; DKFZp564G013 antibody; KIAA1334 antibody; NORPEG antibody; Novel retinal pigment epithelial cell protein antibody; RAI13 antibody; RAI14 antibody; RAI14_HUMAN antibody; Retinoic acid induced 14 antibody; Retinoic acid induced protein 14 antibody; Retinoic acid-induced protein 14 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ankycorbin protein (242-346AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RAI14 Antibody (CSB-PA868376LA01HU)，的标记方式是Non-conjugated。对于RAI14 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA868376LB01HU RAI14 Antibody, HRP conjugated ELISA
    FITC CSB-PA868376LC01HU RAI14 Antibody, FITC conjugated
    Biotin CSB-PA868376LD01HU RAI14 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood-testis barrier.
  • 基因功能参考文献：
    1. TCGA database and Kaplan-Meier Plotter mining results showed that compared to those with RAI14 low mRNA expression levels, Gastric Cancer patients with RAI14 high mRNA expression levels had remarkably lower time of both overall survival and disease-free survival. Cox multivariate survival analyses shows high expression of RAI14 was the only independent predictor of unfavorable prognosis in patients with gastric cancer. PMID: 29654694
    2. Subcellular localization of NORPEG in retinal pigment epithelial (ARPE-19) cells varies with cell density, with predominantly nuclear localization in nonconfluent cells, but a cytoplasmic localization in confluent cultures. PMID: 16729964
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cell junction. Nucleus.
  • 组织特异性：
    Highly expressed in placenta, muscle, kidney and testis. Moderately expressed in heart, brain, lung, liver and intestine. Isoform 2 is widely expressed and expressed in fetal and adult testes, and spermatozoa.
  • 数据库链接：

    HGNC: 14873

    OMIM: 606586

    KEGG: hsa:26064

    STRING: 9606.ENSP00000427123

    UniGene: Hs.431400