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RAB3B Antibody

  • 货号：
    CSB-PA019195LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: RAB3B antibody at 4µg/ml
      Lane 1: Mouse brain tissue
      Lane 2: U87 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 25 kDa
      Observed band size: 25 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA019195LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RAB3B Polyclonal antibody
  • Uniprot No.：
    P20337
  • 基因名：
  • 别名：
    Brain antigen RAB3B antibody; RAB3B antibody; RAB3B member RAS oncogene family antibody; RAB3B_HUMAN antibody; ras related protein Rab 3B antibody; Ras-related protein Rab-3B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Ras-related protein Rab-3B protein (1-219AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RAB3B Antibody (CSB-PA019195LA01HU)，的标记方式是Non-conjugated。对于RAB3B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019195LB01HU RAB3B Antibody, HRP conjugated ELISA
    FITC CSB-PA019195LC01HU RAB3B Antibody, FITC conjugated
    Biotin CSB-PA019195LD01HU RAB3B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Protein transport. Probably involved in vesicular traffic.
  • 基因功能参考文献：
    1. Western blot experiments designed to detect flotillin 2, TMEM256, Rab3B and LAMTOR1 showed that the level of these proteins was higher in urinary exosomes from prostate cancer patients compared to healthy males PMID: 27664330
    2. The structure of Rab3B:GDP complex was solved to 1.9A resolution and the structural base comparison with other Rab3 members provides a structural basis for the GDP/GTP switch in controlling the activity of small GTPase. PMID: 22321395
    3. These results support an important inter-species difference in regulating insulin exocytosis where RAB3B is the most expressed isoform in human islets. PMID: 20807725
    4. RAB3B improves dopamine handling and storage capacity at presynaptic terminals, and confers protection to vulnerable DA neurons. PMID: 20007772
    5. these results add new information to the view that Rab3B is involved in the regulation of pituitary hormone secretion. PMID: 19384079
    6. Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation. PMID: 19717423

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  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 数据库链接：

    HGNC: 9778

    OMIM: 179510

    KEGG: hsa:5865

    STRING: 9606.ENSP00000360718

    UniGene: Hs.123072