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PYGL Antibody

  • 货号：
    CSB-PA830394
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA830394(PYGL Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA830394(PYGL Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 cells, PC3 cells, Primary antibody: CSB-PA830394(PYGL Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P06737
  • 基因名：
  • 别名：
    Glycogen phosphorylase antibody; Glycogen phosphorylase L antibody; Glycogen phosphorylase liver antibody; Glycogen phosphorylase liver form antibody; GSD6 antibody; Hers disease; glycogen storage disease type VI antibody; liver form antibody; OTTHUMP00000233649 antibody; OTTHUMP00000233651 antibody; Phosphorylase glycogen liver antibody; Pygl antibody; PYGL_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human PYGL
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:30-1:150
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
  • 基因功能参考文献：
    1. Susceptibility to excessive liver glycogen storage in patients with type 1 diabetes. PMID: 15223230
    2. Deficiency of liver glycogen phosphorylase is predominantly the result of missense mutations affecting enzyme activity. There are no common mutations and the severity of clinical symptoms varies significantly. PMID: 17705025
  • 相关疾病：
    Glycogen storage disease 6 (GSD6)
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Glycogen phosphorylase family
  • 数据库链接：

    HGNC: 9725

    OMIM: 232700

    KEGG: hsa:5836

    STRING: 9606.ENSP00000216392

    UniGene: Hs.282417