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PTDSS1 Antibody

  • 货号：
    CSB-PA04305A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PTDSS1 antibody at 2µg/ml
      Lane 1: EC109 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 56, 39, 35 kDa
      Observed band size: 35 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA04305A0Rb at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA04305A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PTDSS1 Polyclonal antibody
  • Uniprot No.：
    P48651
  • 基因名：
    PTDSS1
  • 别名：
    PTDSS1 antibody; KIAA0024 antibody; PSSA antibody; Phosphatidylserine synthase 1 antibody; PSS-1 antibody; PtdSer synthase 1 antibody; EC 2.7.8.29 antibody; Serine-exchange enzyme I antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PTDSS1 Antibody (CSB-PA04305A0Rb)，的标记方式是Non-conjugated。对于PTDSS1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA04305B0Rb PTDSS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA04305C0Rb PTDSS1 Antibody, FITC conjugated
    Biotin CSB-PA04305D0Rb PTDSS1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
  • 基因功能参考文献：
    1. RYR2, PTDSS1 and AREG are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease. PMID: 26742492
    2. PSS1 mutations not only affect cellular PS levels and distribution but also lead to a more complex imbalance in lipid homeostasis by disturbing PI4P metabolism. PMID: 27044099
    3. Gain-of-function missense mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome. PMID: 24241535
    4. Purification and characterization of human phosphatidylserine synthases 1 and 2. PMID: 19014349
  • 相关疾病：
    Lenz-Majewski hyperostotic dwarfism (LMHD)
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Phosphatidyl serine synthase family
  • 数据库链接：

    HGNC: 9587

    OMIM: 151050

    KEGG: hsa:9791

    STRING: 9606.ENSP00000430548

    UniGene: Hs.292579