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PSME2 Antibody

  • 货号：
    CSB-PA018916GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UL46
  • 基因名：
  • 别名：
    11S regulator complex beta subunit antibody; 11S regulator complex subunit beta antibody; Activator of multicatalytic protease subunit 2 antibody; Cell migration inducing protein 22 antibody; MCP activator 31 kD subunit antibody; PA28 beta antibody; PA28b antibody; PA28beta antibody; Proteasome (prosome macropain) activator subunit 2 (PA28 beta) antibody; Proteasome (prosome macropain) activator subunit 2 antibody; Proteasome activator 28 beta antibody; Proteasome activator 28 subunit beta antibody; Proteasome activator complex subunit 2 antibody; Proteasome activator hPA28 subunit beta antibody; Proteasome activator subunit 2 antibody; PSME 2 antibody; PSME2 antibody; PSME2_HUMAN antibody; REG beta antibody; REG-beta antibody; REGbeta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PSME2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
  • 基因功能参考文献：
    1. The functional assays demonstrate that PA28beta inhibited cell growth, proliferation and malignancy of TE-1 cells. Among the differentially expressed proteins, PA28b is a potential tumor inhibitor PMID: 29020885
    2. Naa10p suppresses 28S proteasome activity through interaction with PA28beta. PMID: 23624078
    3. knockdown of PA28beta could enhance tumor invasion and metastasis, at least in part, through up-regulation of CLIC1 in gastric adenocarcinoma PMID: 22173998
  • 蛋白家族：
    PA28 family
  • 数据库链接：

    HGNC: 9569

    OMIM: 602161

    KEGG: hsa:5721

    STRING: 9606.ENSP00000216802

    UniGene: Hs.434081