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PSMD5 Antibody

  • 货号：
    CSB-PA618074ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA618074ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA618074ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSMD5 Polyclonal antibody
  • Uniprot No.：
    Q16401
  • 基因名：
    PSMD5
  • 别名：
    26S protease subunit S5 basic antibody; 26S proteasome non-ATPase regulatory subunit 5 antibody; 26S proteasome subunit S5B antibody; Protease 26S; subunit 5B antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase; 5 antibody; Proteasome 19S S5B antibody; Proteasome 26S subunit; non ATPase; 5 antibody; PSMD5 antibody; PSMD5_HUMAN antibody; S5B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 26S proteasome non-ATPase regulatory subunit 5 protein (255-504AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5.
  • 基因功能参考文献：
    1. the critical role of S5b/PSMD5 in negative regulation of proteasome by TNF-alpha/NFkappaB and provide insights into proteasome inhibition in human disease. PMID: 22921402
  • 蛋白家族：
    Proteasome subunit S5B/HSM3 family
  • 数据库链接：

    HGNC: 9563

    OMIM: 604452

    KEGG: hsa:5711

    STRING: 9606.ENSP00000210313

    UniGene: Hs.193725