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PSMB10 Antibody

  • 货号：
    CSB-PA018877ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA018877ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSMB10 Polyclonal antibody
  • Uniprot No.：
    P40306
  • 基因名：
    PSMB10
  • 别名：
    beta2i antibody; FLJ00366 antibody; LMP10 antibody; Low molecular mass protein 10 antibody; Macropain subunit MECl 1 antibody; Macropain subunit MECl-1 antibody; MECL1 antibody; MGC1665 antibody; Multicatalytic endopeptidase complex subunit MECl 1 antibody; Multicatalytic endopeptidase complex subunit MECl-1 antibody; OTTHUMP00000174858 antibody; Proteasome (prosome macropain) subunit beta type 10 antibody; Proteasome beta 10 subunit antibody; Proteasome catalytic subunit 2i antibody; Proteasome MECl 1 antibody; Proteasome MECl-1 antibody; Proteasome subunit beta 2i antibody; Proteasome subunit beta 7i antibody; Proteasome subunit beta type 10 antibody; Proteasome subunit beta type-10 antibody; Proteasome subunit beta-2i antibody; Proteasome subunit MECL1 antibody; PSB10_HUMAN antibody; PSMB 10 antibody; Psmb10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Proteasome subunit beta type-10 protein (1-273AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.
  • 基因功能参考文献：
    1. this study provided novel evidence demonstrating that LMP10 is a positive regulator of NF-kB signaling, which contributes to Ang II-induced retinopathy. PMID: 29499566
    2. LMP10 nuclear expression in the Human Papillomavirus (HPV)-positive group and LMP10 cytoplasmic expression in the HPV-negative group of patients correlated to better clinical outcome. PMID: 24752327
    3. Adenovirus E1A causes down-regulation of MECL1 expression PMID: 22018786
    4. Multicatalytic endopeptidase complex subunit is involved in antigen presentation and is an important candidate gene for initial exploration of relationships between antigen processing genes and disease resistance. PMID: 17541830
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1B family
  • 数据库链接：

    HGNC: 9538

    OMIM: 176847

    KEGG: hsa:5699

    STRING: 9606.ENSP00000351314

    UniGene: Hs.9661