Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. PSMA1 Antibody

PSMA1 Antibody

  • 货号：
    CSB-PA018865LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, PC-3 whole cell lysate, K562 whole cell lysate
      All lanes: PSMA1 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 30, 31 kDa
      Observed band size: 30 kDa
    • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA018865LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA018865LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA018865LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunoprecipitating PSMA1 in K562 whole cell lysate
      Lane 1: Rabbit control IgG (1μg) instead of CSB-PA018865LA01HU in K562 whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the secondary antibody (1/50000)
      Lane 2: CSB-PA018865LA01HU (8μg) + K562 whole cell lysate (500μg)
      Lane 3: K562 whole cell lysate (10μg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSMA1 Polyclonal antibody
  • Uniprot No.：
    P25786
  • 基因名：
    PSMA1
  • 别名：
    30 kDa prosomal protein antibody; HC 2 antibody; HC2 antibody; Macropain subunit C2 antibody; Macropain subunit nu antibody; MGC14542 antibody; MGC14575 antibody; MGC14751 antibody; MGC1667 antibody; MGC21459 antibody; MGC22853 antibody; MGC23915 antibody; Multicatalytic endopeptidase complex subunit C2 antibody; NU antibody; PROS 30 antibody; PROS-30 antibody; PROS30 antibody; Proteasome (prosome macropain) subunit alpha type 1 antibody; Proteasome alpha 1 subunit antibody; Proteasome component C2 antibody; Proteasome nu chain antibody; Proteasome subunit alpha type 1 antibody; Proteasome subunit alpha type I antibody; Proteasome subunit alpha type-1 antibody; Proteasome subunit nu antibody; Protein P30 33K antibody; PSA1_HUMAN antibody; PSC 2 antibody; PSC2 antibody; PSMA 1 antibody; psmA1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Proteasome subunit alpha type-1 protein (163-263AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PSMA1 Antibody (CSB-PA018865LA01HU)，的标记方式是Non-conjugated。对于PSMA1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA018865LB01HU PSMA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA018865LC01HU PSMA1 Antibody, FITC conjugated
    Biotin CSB-PA018865LD01HU PSMA1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
  • 基因功能参考文献：
    1. In thyroid hemiagenesis, genomic examinations revealed the presence of four recurrent defects (three deletions and one duplication) affecting highly conservative proteasome genes PSMA1, PSMA3, and PSMD3. PMID: 28390009
    2. Data indicate that RNA interference screens identified PSMA1, a component of the 20S proteasome as target of non-small cell lung cancer (NSCLC) cytotoxicity. PMID: 24040035
    3. LC/MS/MS analysis revealed that the C-terminal 16 residues of sperm alpha6 subunit are processed. PMID: 21703233
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1A family
  • 数据库链接：

    HGNC: 9530

    OMIM: 602854

    KEGG: hsa:5682

    STRING: 9606.ENSP00000414359

    UniGene: Hs.102798