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PSD4 Antibody

  • 货号：
    CSB-PA843332LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA843332LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA843332LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSD4 Polyclonal antibody
  • Uniprot No.：
    Q8NDX1
  • 基因名：
  • 别名：
    EFA6B antibody; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B antibody; FLJ36237 antibody; FLJ37279 antibody; PH and SEC7 domain-containing protein 4 antibody; Pleckstrin homology and SEC7 domain-containing protein 4 antibody; Ppleckstrin and Sec7 domain containing 4 antibody; PSD4 antibody; PSD4_HUMAN antibody; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein antibody; Telomeric of interleukin-1 cluster protein antibody; TIC antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PSD4 Antibody (CSB-PA843332LA01HU)，的标记方式是Non-conjugated。对于PSD4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA843332LB01HU PSD4 Antibody, HRP conjugated ELISA
    FITC CSB-PA843332LC01HU PSD4 Antibody, FITC conjugated
    Biotin CSB-PA843332LD01HU PSD4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
  • 基因功能参考文献：
    1. results identify EFA6B as a novel antagonist in breast cancer and they point to its regulatory and signaling pathways as rational therapeutic targets in aggressive forms of this disease PMID: 25115298
    2. One of the cytohesin family of guanine nucleotide exchange factors, Tic may act on the ARF family of GTP-binding proteins. A PH domain with similar sequence and relative position to those in other cytohesins may allow association with phosphoinositides. PMID: 11050434
  • 亚细胞定位：
    Cell membrane. Cell projection, ruffle membrane.
  • 组织特异性：
    Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
  • 数据库链接：

    HGNC: 19096

    OMIM: 614442

    KEGG: hsa:23550

    STRING: 9606.ENSP00000245796

    UniGene: Hs.516306