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PRTFDC1 Antibody

  • 货号：
    CSB-PA889092LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA889092LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA889092LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PRTFDC1 Polyclonal antibody
  • Uniprot No.：
    Q9NRG1
  • 基因名：
    PRTFDC1
  • 别名：
    FLJ11888 antibody; HHGP antibody; OTTHUMP00000019332 antibody; Phosphoribosyl transferase domain containing 1 antibody; phosphoribosyltransferase domain containing protein 1 antibody; Phosphoribosyltransferase domain-containing protein 1 antibody; PRDC1_HUMAN antibody; prtfdc1 antibody; Uncharacterized protein PRTFDC1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Phosphoribosyltransferase domain-containing protein 1 (2-225AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PRTFDC1 Antibody (CSB-PA889092LA01HU)，的标记方式是Non-conjugated。对于PRTFDC1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA889092LB01HU PRTFDC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA889092LC01HU PRTFDC1 Antibody, FITC conjugated
    Biotin CSB-PA889092LD01HU PRTFDC1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
  • 基因功能参考文献：
    1. We found evidence for PRTFDC1 as a potential novel PTSD gene, a finding that awaits further replication. PMID: 25456346
    2. These results demonstrate that PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PMID: 21818316
    3. The PRTFDC1 structure has been determined at 1.7 A resolution with bound GMP. The overall structure and GMP binding mode are very similar to that observed for HPRT. PMID: 21054786
    4. epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PMID: 17599052
  • 蛋白家族：
    Purine/pyrimidine phosphoribosyltransferase family
  • 数据库链接：

    HGNC: 23333

    OMIM: 610751

    KEGG: hsa:56952

    STRING: 9606.ENSP00000318602

    UniGene: Hs.405619