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PRSS56 Antibody

  • 货号：
    CSB-PA317372LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Rat liver tissue, Rat spleen tissue
      All lanes: PRSS56 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 65 kDa
      Observed band size: 65 kDa
    • Immunohistochemistry of paraffin-embedded human eye tissue using CSB-PA317372LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PRSS56 Polyclonal antibody
  • Uniprot No.：
    P0CW18
  • 基因名：
    PRSS56
  • 别名：
    PRSS56 antibody; Serine protease 56 antibody; EC 3.4.21.- antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Serine protease 56 protein (36-116AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PRSS56 Antibody (CSB-PA317372LA01HU)，的标记方式是Non-conjugated。对于PRSS56 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA317372LB01HU PRSS56 Antibody, HRP conjugated ELISA
    FITC CSB-PA317372LC01HU PRSS56 Antibody, FITC conjugated
    Biotin CSB-PA317372LD01HU PRSS56 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Serine protease required during eye development.
  • 基因功能参考文献：
    1. variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia. PMID: 24227917
    2. Idenification of a founder mutation in the PRSS56 gene in Tunisian families with posterior microphthalmia and nanophthalmia. PMID: 23820083
    3. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause. PMID: 23127749
    4. PRSS56 is a good candidate for the causal gene for nanophthalmos in a Mexican-Canadian family cohort. PMID: 21850159
    5. Together, these data suggest that alterations of this serine protease may contribute to a spectrum of human ocular conditions including reduced ocular size and ACG. PMID: 21532570
    6. Three different mutations in PRSS56, were detected in microphthalmos patients of the Faroese families. PMID: 21397065

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  • 相关疾病：
    Microphthalmia, isolated, 6 (MCOP6)
  • 蛋白家族：
    Peptidase S1 family
  • 组织特异性：
    Expressed neural retina, cornea, sclera and optic nerve.
  • 数据库链接：

    HGNC: 39433

    OMIM: 613517

    KEGG: hsa:646960

    UniGene: Hs.570310