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PRICKLE2 Antibody

  • 货号：
    CSB-PA773783ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA773783ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA773783ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PRICKLE2 Polyclonal antibody
  • Uniprot No.：
    Q7Z3G6
  • 基因名：
  • 别名：
    EPM5 antibody; PRIC2 antibody; PRIC2_HUMAN antibody; Prickle homolog 2 (Drosophila) antibody; Prickle planar cell polarity protein 2 antibody; prickle-like 2 (Drosophila) antibody; prickle-like 2 antibody; Prickle-like protein 2 antibody; PRICKLE2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Prickle-like protein 2 protein (615-844AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. 2 autism-spectrum-disorder patients had distinct, paternally inherited, heterozygous, non-synonymous PRICKLE2 variants (p.E8Q and p.V153I) shared by their affected siblings. These variants had deficits in morphological and electrophysiological assays. PMID: 23711981
  • 相关疾病：
    PRICKLE2 mutations have been found in patients with myoclonic epilepsy but involvement of this gene in pathogenesis is under debate since some of the patients also carry POLG mutations.
  • 亚细胞定位：
    Nucleus membrane.
  • 蛋白家族：
    Prickle / espinas / testin family
  • 组织特异性：
    Expressed in brain, eye and testis. Additionally in fetal brain, adult cartilage, pancreatic islet, gastric cancer and uterus tumors.
  • 数据库链接：

    HGNC: 20340

    OMIM: 608501

    KEGG: hsa:166336

    STRING: 9606.ENSP00000295902

    UniGene: Hs.148105