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PRDM12 Antibody

  • 货号：
    CSB-PA003849
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using PRDM12 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9H4Q4
  • 基因名：
    PRDM12
  • 别名：
    PRDM12 antibody; PFM9PR domain zinc finger protein 12 antibody; EC 2.1.1.- antibody; PR domain-containing protein 12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PRDM12.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the positive regulation of histone H3-K9 dimethylation.
  • 基因功能参考文献：
    1. The natural history of the PRDM12-CIP disorder. PMID: 26975306
    2. PRDM12 and its functional fly homolog Hamlet are evolutionary conserved master regulators of sensory neuronal specification and play a critical role in pain perception PMID: 25891934
    3. Prdm12 is a key factor in the orchestration of sensory neurogenesis. PMID: 26005867
    4. Down-regulation of PRDM12 is associated with the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion PMID: 14523459
  • 相关疾病：
    Neuropathy, hereditary sensory and autonomic, 8 (HSAN8)
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Class V-like SAM-binding methyltransferase superfamily
  • 组织特异性：
    Not found in adult tissues except in dorsal root ganglia.
  • 数据库链接：

    HGNC: 13997

    OMIM: 616458

    KEGG: hsa:59335

    UniGene: Hs.495311