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PPP2R2C Antibody

  • 货号：
    CSB-PA018566GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2T4
  • 基因名：
  • 别名：
    2ABG_HUMAN antibody; B55 gamma antibody; Gamma isoform of regulatory subunit B55 protein phosphatase 2 antibody; IMYPNO 1 antibody; IMYPNO antibody; IMYPNO1 antibody; MGC33570 antibody; OTTHUMP00000115505 antibody; Phosphoprotein phosphatase 2A BR gamma regulatory chain antibody; PP2A subunit B B gamma isoform antibody; PP2A subunit B B55 gamma isoform antibody; PP2A subunit B isoform B55-gamma antibody; PP2A subunit B isoform gamma antibody; PP2A subunit B isoform PR55-gamma antibody; PP2A subunit B isoform R2-gamma antibody; PP2A subunit B PR55 gamma isoform antibody; PP2A subunit B R2 gamma isoform antibody; PPP2R2C antibody; PPP2R2C protein antibody; PR 52 antibody; PR 55G antibody; PR52 antibody; PR55G antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform antibody; Protein phosphatase 2 regulatory subunit B gamma antibody; Protein phosphatase 2 regulatory subunit B gamma isoform antibody; Protein phosphatase 2A1 B gamma subunit antibody; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PPP2R2C
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能参考文献：
    1. B55gamma is induced by glucocorticoid receptor in human primary BM-MSCs during differentiation to osteoblast and is required for osteoblast morphogenesis. PMID: 28805158
    2. miR-572 promotes the proliferation and invasion of nasopharyngeal carcinoma by directly down-regulating PPP2R2C PMID: 28525724
    3. miR-1301 promoted prostate cancer proliferation by inhibiting PPP2R2C. PMID: 27261573
    4. These findings provide insights into mechanisms by which prostate cancers resist AR-pathway suppression and support inhibiting PPP2R2C complexes. PMID: 23493267
    5. PPP2R2C is a potential tumor suppressor gene in human brain cancers. PMID: 24126060
    6. evidence suggests that allelic variation in PPP2R2C may be associated with a variety of personality traits and ADHD per se. PMID: 22664926
    7. encoding a subunit of proteinphosphatase 2A with a unique expression pattern in brain and a role in synaptic plasticity PMID: 20601260
    8. specific PP2A complexes involved in human cell transformation PMID: 14998489
    9. novel mechanism of c-SRC regulation whereby in response to stress c-SRC activity is regulated, at least in part, through loss of the interaction with its inhibitor, PR55gamma PMID: 18069897

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  • 蛋白家族：
    Phosphatase 2A regulatory subunit B family
  • 数据库链接：

    HGNC: 9306

    OMIM: 605997

    KEGG: hsa:5522

    STRING: 9606.ENSP00000335083

    UniGene: Hs.479069