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PPP1R14B Antibody

  • 货号：
    CSB-PA008762
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96C90
  • 基因名：
    PPP1R14B
  • 别名：
    PHI 1 antibody; PHI1 antibody; Phospholipase C beta 3 neighboring gene protein antibody; Phospholipase C beta 3 neighbouring gene protein antibody; Phospholipase C-beta-3 neighbouring gene protein antibody; PLCB3N antibody; PNG antibody; PP14B_HUMAN antibody; Ppp1r14b antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 14B antibody; Protein phosphatase 1 regulatory subunit 14B antibody; SOM172 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PHI-1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.
  • 基因功能参考文献：
    1. Whereas CPI-17 staining was diffuse, PHI-1 was concentrated along the cell membrane in distinct foci. The common tissue distribution but different cellular localization of PHI-1 and CPI-17 suggest distinctive physiological roles for these PP1 inhibitors. PMID: 15083373
    2. PHI-1 participates in regulatory events at the trailing edge of migrating cells and modulates retraction of endothelial and epithelial cells PMID: 15522888
    3. An inhibitory phosphoprotein that inhibits the myosin- and glycogen-associated holoenzyme versions of protein type-1 phosphatase (PP1) as well as the monomeric catalytic subunit of PP1 in multiple tissues. PMID: 10606530
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    PP1 inhibitor family
  • 组织特异性：
    Ubiquitous. Expressed at low levels.
  • 数据库链接：

    HGNC: 9057

    OMIM: 601140

    KEGG: hsa:26472

    STRING: 9606.ENSP00000310117

    UniGene: Hs.523760