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PPCS Antibody

  • 货号：
    CSB-PA018434GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9HAB8
  • 基因名：
    PPCS
  • 别名：
    COAB antibody; FLJ11838 antibody; MGC117357 antibody; MGC138220 antibody; OTTHUMP00000008433 antibody; Phosphopantothenate--cysteine ligase antibody; Phosphopantothenoylcysteine synthetase antibody; PPC synthetase antibody; Ppcs antibody; PPCS_HUMAN antibody; RP11-163G10.1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PPCS
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the second step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. Has a preference for ATP over CTP as a cosubstrate.
  • 基因功能参考文献：
    1. Exome sequencing in five individuals from two unrelated families presenting with dilated cardiomyopathy revealed biallelic mutations in PPCS. PMID: 29754768
    2. Oxygen transfer studies found that 18O from [carboxyl-18O] phosphopantothenate is incorporated into AMP or CMP produced during PPCS catalysis, consistent with the formation of a phosphopantothenoyl cytidylate or phosphopantothenoyl adenylate intermediate PMID: 19683078
  • 蛋白家族：
    PPC synthetase family
  • 数据库链接：

    HGNC: 25686

    OMIM: 609853

    KEGG: hsa:79717

    STRING: 9606.ENSP00000361642

    UniGene: Hs.706662