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  4. POLR3K Antibody

POLR3K Antibody

  • 货号：
    CSB-PA018352GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2Y1
  • 基因名：
    POLR3K
  • 别名：
    C11 antibody; C11 RNP3 antibody; DNA directed RNA polymerase III subunit K antibody; DNA directed RNA polymerase III subunit RPC10 antibody; DNA directed RNA polymerases III 12.5 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit K antibody; DNA-directed RNA polymerase III subunit RPC10 antibody; hRPC11 antibody; HsC11p antibody; My010 antibody; POLR3K antibody; Polymerase (RNA) III (DNA directed) polypeptide K antibody; Polymerase (RNA) III (DNA directed) polypeptide K; 12.3 kDa antibody; RNA polymerase III 12.5 kDa subunit antibody; RNA polymerase III subunit (hRPC11) antibody; RNA polymerase III subunit C10 antibody; RNA polymerase III subunit C11 antibody; RNA polymerase III subunit CII antibody; RPC10 antibody; RPC10_HUMAN antibody; RPC11 antibody; RPC12.5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human POLR3K
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
  • 基因功能参考文献：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that POLR3K is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. Changes in Maf1 expression affect Pol III-dependent transcription in human glioblastoma lines. PMID: 17499043
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
  • 数据库链接：

    HGNC: 14121

    OMIM: 606007

    KEGG: hsa:51728

    STRING: 9606.ENSP00000293860

    UniGene: Hs.632223