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POLR1E Antibody

  • 货号：
    CSB-PA050039
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9GZS1
  • 基因名：
    POLR1E
  • 别名：
    A49 antibody; DNA directed RNA polymerase I subunit RPA49 antibody; DNA-directed RNA polymerase I subunit E antibody; DNA-directed RNA polymerase I subunit RPA49 antibody; FLJ 13390 antibody; FLJ13970 antibody; PAF53 antibody; POLR 1 E antibody; POLR1E antibody; Polymerase (RNA) I associated factor 1 antibody; Polymerase (RNA) I polypeptide E antibody; Polymerase (RNA) I polypeptide E, 53kDa antibody; PRAF1 antibody; RNA polymerase I associated factor 1 antibody; RNA polymerase I associated factor 53 antibody; RNA polymerase I polypeptide E antibody; RNA polymerase I subunit A49 antibody; RNA polymerase I-associated factor 1 antibody; RNA polymerase I-associated factor 53 antibody; RP11405L18.3 antibody; RPA49_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human POLR1E.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.
  • 基因功能参考文献：
    1. Nucleolar detention requires binding of SIRT7 to nascent pre-rRNA, linking the spatial distribution of SIRT7 and deacetylation of PAF53 to ongoing transcription. PMID: 24207024
  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Eukaryotic RPA49/POLR1E RNA polymerase subunit family
  • 数据库链接：

    HGNC: 17631

    KEGG: hsa:64425

    STRING: 9606.ENSP00000367029

    UniGene: Hs.591087