POLE2 Antibody
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货号:CSB-PA004689
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规格:¥880
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图片:
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其他:
产品详情
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Uniprot No.:P56282
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基因名:
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别名:DNA polymerase epsilon subunit 2 antibody; DNA polymerase epsilon subunit B antibody; DNA polymerase II subunit 2 antibody; DPE 2 antibody; DPE2 antibody; DPOE2_HUMAN antibody; POLE 2 antibody; POLE2 antibody; Polymerase (DNA directed) epsilon 2 (p59 subunit) antibody; Polymerase (DNA directed) epsilon 2 antibody; polymerase (DNA directed); epsilon 2; accessory subunit antibody; Polymerase; DNA; epsilon-2 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Synthesized peptide derived from the Internal region of Human DNA pol ε B.
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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抗体亚型:IgG
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纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式:Liquid
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应用范围:WB, ELISA
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:40000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
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基因功能参考文献:
- found that mutations occurred in POLE2 in 5 out of 16 cases of human colon cancer examined. PMID: 20065316
- The solution structure of the N-terminal domain of human DNA polymerase epsilon subunit B revealed a domain that consists of a left-handed superhelical bundle. PMID: 18676977
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亚细胞定位:Nucleus.
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蛋白家族:DNA polymerase epsilon subunit B family
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数据库链接:
HGNC: 9178
OMIM: 602670
KEGG: hsa:5427
STRING: 9606.ENSP00000216367
UniGene: Hs.162777
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