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PODXL2 Antibody

  • 货号：
    CSB-PA315869
  • 规格：
    ￥880
  • 图片：
    • Western blot analysis of Hela using Endoglycan antibody.. Secondary antibody was diluted at 1:20000
  • 其他：

产品详情

  • Uniprot No.：
    Q9NZ53
  • 基因名：
    PODXL2
  • 别名：
    PODXL2 antibody; UNQ1861/PRO3742 antibody; Podocalyxin-like protein 2 antibody; Endoglycan antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Endoglycan.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
  • 基因功能参考文献：
    1. endoglycan functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x PMID: 12889478
    2. findings indicate that endoglycan can function as a ligand for the vascular selectins. PMID: 18606703
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Podocalyxin family
  • 组织特异性：
    Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in live
  • 数据库链接：

    HGNC: 17936

    OMIM: 616627

    KEGG: hsa:50512

    STRING: 9606.ENSP00000345359

    UniGene: Hs.591290