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PLGRKT Antibody

  • 货号：
    CSB-PA875713LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PLGRKT antibody at 6μg/ml
      Lane 1: A431 whole cell lysate
      Lane 2: Mouse lung tissue
      Lane 3: NIH/3T3 whole cell lysate
      Lane 4: U251 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 18 kDa
      Observed band size: 18 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA875713LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA875713LA01HU at dilution of 1:100
    • Immunofluorescent analysis of U251 cells using CSB-PA875713LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品描述：

    CUSABIO immunizes the rabbit with a peptide corresponding to amino acids 1-147 of the human PLGRKT protein to yield the anti-PLGRKT antibody. The PLGRKT antibody exists as an unconjugated IgG isotype. Its purity is greater than 95% using protein G purified. This PLGRKT antibody can recognize the PLGRKT protein in ELISA, WB, IHC, and IF applications and shows reactivity with human and mouse samples. Its target protein PLGRKT is a transmembrane plasminogen receptor that promotes plasminogen activation to plasmin by plasminogen activators on cell surfaces and acts as a modulator involved in different phases of cutaneous burn wound healing through its effects in the interrelated responses of inflammation, keratinocyte migration, and fibrinolysis.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PLGRKT Polyclonal antibody
  • Uniprot No.：
    Q9HBL7
  • 基因名：
    PLGRKT
  • 别名：
    PLGRKT; C9orf46; AD025; MDS030; Plasminogen receptor; KT; Plg-R(KT
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Plasminogen receptor (KT) protein (1-147AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PLGRKT Antibody (CSB-PA875713LA01HU)，的标记方式是Non-conjugated。对于PLGRKT Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA875713LB01HU PLGRKT Antibody, HRP conjugated ELISA
    FITC CSB-PA875713LC01HU PLGRKT Antibody, FITC conjugated
    Biotin CSB-PA875713LD01HU PLGRKT Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metalloproteinase activation, such as of MMP2 and MMP9.
  • 基因功能参考文献：
    1. Plg-R(KT) was highly expressed in bovine adrenomedullary chromaffin cells, human pheochromocytoma tissue, PC12 pheochromocytoma cells, and murine hippocampus. PMID: 21795689
    2. Plg-R(KT) plays a key role in the plasminogen-dependent regulation of macrophage invasion, chemotactic migration, and recruitment in the inflammatory response. PMID: 21940822
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 组织特异性：
    Expressed in peripheral blood cells and monocytes. Expressed in adrenal medulla.
  • 数据库链接：

    HGNC: 23633

    KEGG: hsa:55848

    STRING: 9606.ENSP00000223864

    UniGene: Hs.584242