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PLD4 Antibody

  • 货号：
    CSB-PA006980
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using PC-PLD4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q96BZ4
  • 基因名：
    PLD4
  • 别名：
    C14orf175 antibody; Choline phosphatase 4 antibody; EC 3.1.4.4 antibody; Phosphatidylcholine hydrolyzing phospholipase D4 antibody; Phosphatidylcholine-hydrolyzing phospholipase D4 antibody; Phospholipase D family member 4 antibody; Phospholipase D4 antibody; PLD 4 antibody; PLD4 antibody; PLD4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human PC-PLD4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
  • 基因功能参考文献：
    1. PLD4 expression in colon cancer tissues PMID: 27840999
    2. We determined that PLD4 is a novel susceptibility gene for sysetmic sclerosis in Japanese, thus confirming the involvement of PLD4 in autoimmunity. PMID: 23124809
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome.
  • 蛋白家族：
    Phospholipase D family
  • 数据库链接：

    HGNC: 23792

    KEGG: hsa:122618

    STRING: 9606.ENSP00000376372

    UniGene: Hs.407101