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PITPNB Antibody

  • 货号：
    CSB-PA018036GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P48739
  • 基因名：
    PITPNB
  • 别名：
    OTTHUMP00000198846 antibody; OTTHUMP00000198847 antibody; Phosphatidylinositol transfer protein beta isoform antibody; Phosphatidylinositol transfer protein, beta antibody; PI TP beta antibody; PI-TP-beta antibody; PIPNB_HUMAN antibody; Pitpnb antibody; PtdIns transfer protein beta antibody; PtdInsTP antibody; PtdInsTP beta antibody; VIB1B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PITPNB
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function.
  • 基因功能参考文献：
    1. Phosphatidylinositol and phosphatidylcholine exchange activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum. PMID: 20332109
    2. Role of PITPNB- not required for sphingomyelin trafficking PMID: 12023904
    3. The presence of PITPbeta splice variants adds an extra level of proteome complexity PMID: 16780419
  • 亚细胞定位：
    Golgi apparatus. Golgi apparatus membrane. Endoplasmic reticulum membrane.
  • 蛋白家族：
    PtdIns transfer protein family, PI transfer class I subfamily
  • 组织特异性：
    Widely expressed in various tissues including brain.
  • 数据库链接：

    HGNC: 9002

    OMIM: 606876

    KEGG: hsa:23760

    STRING: 9606.ENSP00000334738

    UniGene: Hs.705323