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PIK3IP1 Antibody

  • 货号：
    CSB-PA850293LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue
      All lanes: PIK3IP1 antibody at 7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29, 26, 12, 19, 20 kDa
      Observed band size: 29 kDa
    • Immunofluorescence staining of Hela cells with CSB-PA850293LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PIK3IP1 Polyclonal antibody
  • Uniprot No.：
    Q96FE7
  • 基因名：
    PIK3IP1
  • 别名：
    HGFL antibody; hHGFL(S) antibody; Kringle domain containing protein HGFL antibody; Kringle domain-containing protein HGFL antibody; MGC17330 antibody; P3IP1_HUMAN antibody; Phosphoinositide 3 kinase interacting protein 1 antibody; Phosphoinositide-3-kinase-interacting protein 1 antibody; PIK3IP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Phosphoinositide-3-kinase-interacting protein 1 protein (22-168AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PIK3IP1 Antibody (CSB-PA850293LA01HU)，的标记方式是Non-conjugated。对于PIK3IP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA850293LB01HU PIK3IP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA850293LC01HU PIK3IP1 Antibody, FITC conjugated
    Biotin CSB-PA850293LD01HU PIK3IP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity.
  • 基因功能参考文献：
    1. Findings indicate that colon cancer associated transcript 1 (non-protein coding) (CCAT1) was upregulated in osteosarcoma tissues and cells, and was involved in the proliferation and migration of osteosarcoma via regulating miR-148a/phosphatidyl inositol 3-kinase interacting protein 1 (PIK3IP1) signal pathway. PMID: 28549102
    2. These results suggest that the novel PI3K regulator PIK3IP1 plays an inhibitory role in T-cell activation. PMID: 22706993
    3. PIK3IP1-v1 is a novel splicing isoform of PIK3IP1. Both of them are located on cell membrane and can induce cell apoptosis. PMID: 19088825
    4. PIK3IP1 directly binds to the p110 catalytic subunit and down modulates PI3K activity. Suggested that PIK3IP1 is a new type of PI3K regulator. PMID: 17475214
    5. PIK3IP1 is an important regulator of PI3K in vivo, and its dysregulation can contribute to liver carcinogenesis PMID: 18632611

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 数据库链接：

    HGNC: 24942

    KEGG: hsa:113791

    STRING: 9606.ENSP00000215912

    UniGene: Hs.26670