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PFDN5 Antibody

  • 货号：
    CSB-PA017815GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q99471
  • 基因名：
    PFDN5
  • 别名：
    1190001O17Rik antibody; 1700010A06Rik antibody; c myc binding protein antibody; c-myc binding protein MM 1 antibody; C-myc-binding protein Mm-1 antibody; D15Ertd697e antibody; EIG 1 antibody; Eig1 antibody; MGC5329 antibody; MGC71907 antibody; MM 1 antibody; MM1 antibody; Myc modulator 1 antibody; PFD5 antibody; PFD5_HUMAN antibody; PFDN5 antibody; Prefoldin 5 antibody; Prefoldin subunit 5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PFDN5
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
  • 基因功能参考文献：
    1. Results from a study on gene expression variability markers in early-stage human embryos shows that PFDN5 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. interaction with p73 PMID: 11844794
    3. MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc PMID: 16173081
    4. Wnt4 gene, a member of the Wnt-beta-catenin pathway, was identified as a target gene of MM-1. PMID: 18281035
  • 亚细胞定位：
    [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.
  • 蛋白家族：
    Prefoldin subunit alpha family
  • 组织特异性：
    Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
  • 数据库链接：

    HGNC: 8869

    OMIM: 604899

    KEGG: hsa:5204

    STRING: 9606.ENSP00000334188

    UniGene: Hs.655327