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PDP2 Antibody

  • 货号：
    CSB-PA004699
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9P2J9
  • 基因名：
    PDP2
  • 别名：
    [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 antibody; KIAA1348 antibody; mitochondrial antibody; PDP 2 antibody; Pdp2 antibody; PDP2_HUMAN antibody; PDPC 2 antibody; PPM2B antibody; PPM2C2 antibody; Protein phosphatase 2C magnesium dependent catalytic subunit 2 antibody; Protein phosphatase Mg2+/Mn2+ dependent 2B antibody; Pyruvate dehydrogenase phosphatase 2 antibody; Pyruvate dehydrogenase phosphatase catalytic subunit 2 antibody; pyruvate dehydrogenase phosphatase isoenzyme 2 antibody; Pyruvate dehydrogenase phosphatase; catalytic subunit 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PDP2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
  • 基因功能参考文献：
    1. ICER was found to bind to the Pdp2 promoter and suppress its expression. Furthermore, forced expression of PDP2 in CD4(+) cells reduced the in vitro Th17 differentiation, whereas shRNA-based suppression of PDP2 expression increased in vitro Th17 differentiation PMID: 30150402
    2. catalytic subunit of PDP2 crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 53.6, b = 69.1, c = 109.7 A. PMID: 20208177
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    PP2C family
  • 数据库链接：

    HGNC: 30263

    OMIM: 615499

    KEGG: hsa:57546

    STRING: 9606.ENSP00000309548

    UniGene: Hs.632214