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PCYOX1 Antibody

  • 货号：
    CSB-PA017652GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UHG3
  • 基因名：
    PCYOX1
  • 别名：
    EC 1.8.3.5 antibody; KIAA0908 antibody; PCL1 antibody; PCYOX_HUMAN antibody; PCYOX1 antibody; Prenylcysteine lyase antibody; Prenylcysteine oxidase 1 antibody; Prenylcysteine oxidase precursor antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PCYOX1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.
  • 基因功能参考文献：
    1. Elevated prenylcysteine oxidase 1 (PCYOX1) activity could help to propagate the oxidative burden of low density lipoproteins (LDLs), thus making PCYOX1 a potential pharmacological target and a new biomarker in cardiovascular disease [Review]. PMID: 28930587
    2. initial studies of the kinetic mechanism and stereospecificity of this unusual enzyme PMID: 12186880
    3. Addition of the substrate farnesylcysteine to lipoprotein resulted in a time-dependent generation of H(2)O(2) which was stronger in very low density lipoprotein (VLDL) than in LDL or HDL, reflecting the greater protein content of PCL1 in VLDL. PMID: 19253276
  • 亚细胞定位：
    Lysosome.
  • 蛋白家族：
    Prenylcysteine oxidase family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 20588

    OMIM: 610995

    KEGG: hsa:51449

    STRING: 9606.ENSP00000387654

    UniGene: Hs.567502