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PARP4 Antibody

  • 货号：
    CSB-PA007321
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKK3
  • 基因名：
  • 别名：
    PARP4 antibody; ADPRTL1 antibody; KIAA0177 antibody; PARPL antibody; Protein mono-ADP-ribosyltransferase PARP4 antibody; EC 2.4.2.- antibody; 193 kDa vault protein antibody; ADP-ribosyltransferase diphtheria toxin-like 4 antibody; ARTD4 antibody; PARP-related/IalphaI-related H5/proline-rich antibody; PH5P antibody; Poly [ADP-ribose] polymerase 4 antibody; PARP-4 antibody; Vault poly(ADP-ribose) polymerase antibody; VPARP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PARP-4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
  • 基因功能参考文献：
    1. Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP for full activity PMID: 28551640
    2. PARP4 is a possible susceptibility gene of primary thyroid and breast cancer PMID: 26699384
    3. the protein levels of MVP, TEP1 and vPARP are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production. PMID: 23739867
    4. REVIEW:recent findings suggesting that PARP-1 participates in DNA damage signaling in cell death PMID: 12829019
  • 亚细胞定位：
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
  • 组织特异性：
    Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.
  • 数据库链接：

    HGNC: 271

    OMIM: 607519

    KEGG: hsa:143

    STRING: 9606.ENSP00000371419

    UniGene: Hs.744855