P Antibody
产品详情
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产品名称:Rabbit anti-Hepatitis B virus genotype A2 subtype adw2 P Polyclonal antibody
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Uniprot No.:P17100
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基因名:P
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别名:PProtein P [Includes: DNA-directed DNA polymerase antibody; EC 2.7.7.7); RNA-directed DNA polymerase antibody; EC 2.7.7.49); Ribonuclease H antibody; EC 3.1.26.4)] antibody
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宿主:Rabbit
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反应种属:Hepatitis B virus genotype A2 subtype adw2
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免疫原:Recombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA)
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免疫原种属:Hepatitis B virus genotype A2 subtype adw2
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标记方式:Non-conjugated
本页面中的产品,P Antibody (CSB-PA324598LA01HDO),的标记方式是Non-conjugated。对于P Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
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蛋白家族:Hepadnaviridae P protein family
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