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Ovotransferrin Antibody

  • 货号：
    CSB-PA00390E0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品描述：

    The chicken Ovotransferrin (Otrf) is used as the immunogen to immunize the rabbit to yield the anti-Ovotransferrin antibody. The Ovotransferrin polyclonal antibody exhibits as an unconjugated IgG isoform. Its purity is 95%+ using protein G purified. It only reacts with chicken Ovotransferrin, which is present both in avian plasma and egg white and possesses both iron-transfer and protective properties. Ovotransferrin is responsible for promoting the growth and development of the chicken embryo mainly by preventing the growth of microorganisms together with other proteins such as lysozyme, cystatin, and avidin. This Ovotransferrin antibody has been validated to recognize Ovotransferrin in ELISA analysis.

  • 产品名称：
    Rabbit anti-Chicken N/A Polyclonal antibody
  • Uniprot No.：
    P02789
  • 基因名：
    N/A
  • 别名：
    Ovotransferrin antibody; Allergen Gal d III antibody; Conalbumin antibody; Serum transferrin antibody; allergen Gal d 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Chicken
  • 免疫原：
    Chicken Ovotransferrin (Native Protein)
  • 免疫原种属：
    Chicken
  • 标记方式：
    Non-conjugated

    本页面中的产品，Ovotransferrin Antibody (CSB-PA00390E0Rb)，的标记方式是Non-conjugated。对于Ovotransferrin Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA00390F0Rb Ovotransferrin Antibody, HRP conjugated ELISA
    FITC CSB-PA00390G0Rb Ovotransferrin Antibody, FITC conjugated
    Biotin CSB-PA00390H0Rb Ovotransferrin Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels.
  • 基因功能参考文献：
    1. unfolding pathway and conformational stability of conalbumin PMID: 21833676
    2. glycosylation of fetal & hen ovotransferrin differs; hypothesized to alter ovotransferrin recognition by carbohydrate binding lectins PMID: 7881176
    3. studied the carbohydrate and amino acid compositions of the ovotransferrin glycopeptides PMID: 574451
    4. The exon structure of the ovotransferrin gene confirms the duplication event to produce two homologous domains that make up ovotransferrin PMID: 3658709
    5. evidence suggests that conalbumin (ovotransferrin) and transferrin are products of the same gene, differing only in carbohydrate content PMID: 4907959
    6. show both lobes are required for efficient iron binding and calculate binding kinetics. PMID: 6319414
    7. ovotransferrin folds into two compact, iron-binding domains; the s demonstrate that the duplicated domain structure is necessary to retain ovotransferrin in plasma and stop immediate loss via kidney filtration PMID: 6805466
    8. The structure of ovotransferrin shows that the iron-binding site is located in the interdomain cleft in each lobe; differences in ovotransferrin structure cause changes to iron binding & uptake/release compared to lactotransferrin & transferrin. PMID: 7490743
    9. At a pH where the protein net charge is negative (pH 8.0), the behavior of ovotransferrin at the air-water interface is more influenced by charge effects rather than bulk concentration effects. PMID: 21316692
    10. Trp-Asn-Ile-Pro and Gly-Trp-Asn-Ile peptides of ovotransferrin showed the highest antioxidant activity. PMID: 20568771
    11. Marked stabilization effects by amino(N)- and carboxyl(C)-terminal lobes of ovotransferrin are induced during iron binding, primarily upon N-lobe iron binding in the iron-free C-lobe and secondarily upon C-lobe iron binding in the monoferric N-lobe. PMID: 15323571
    12. Ovotransferrin is able to cleave itself through the unique chemical reactivity of four tripeptides motifs, HTT (residues 209-211), HST (residues 542-544) and two CHT (residues 115-117 and 454-456). PMID: 16442235
    13. Several proteins associated with the egg shell membranes (ESM) with antibacterial activity have been identified including ovotransferrin, in addition, pure fractions of ovotransferrin were obtained from egg white. PMID: 16721662

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Transferrin family
  • 组织特异性：
    Expressed in the magnum of the oviduct (at protein level).
  • 数据库链接：

    KEGG: gga:396241

    UniGene: Gga.2551